Here are the biggest injuries in Week 17:
Will Fuller V, WR, Houston Texans: Fuller, who was expected to have an elevated role in Week 17 due to DeAndre Hopkins being out of the lineup, was ruled out of the game early in the first quarter after aggravating a knee injury.
Jonathan Cooper, OG, Dallas Cowboys: Cooper remained down after a play late in the first half, and was helped off the field and into the locker room to have his left knee examined. Joe Looney replaced him in the lineup.
Marcus Maye, S, New York Jets: During a play on which he was penalized for pass interference against Brandin Cooks, Maye appeared to injure his foot or ankle, and was brought back to the locker room for testing. He was declared questionable to return due to a right ankle injury. During the third quarter, the Jets downgraded Maye to out.
Teez Tabor, CB, Detroit Lions: Tabor injured his arm during the first quarter, and was brought directly to the locker room for further testing. The Lions declared him questionable to return due to the arm injury. Early in the second half, Tabor was downgraded to out.
Geronimo Allison, WR, Green Bay Packers: Allison injured a finger on his right hand during the first quarter. After having it looked at on the sideline, he retreated to the locker room. The Packers declared him questionable to return.
Don Carey, S, Detroit Lions: Carey went down in the first quarter with what appeared to be a right leg injury. He was attended to on the field and required assistance getting to the sideline before heading to the locker room. Carey was ruled out due to a knee injury.
Samaje Perine, RB, Washington Redskins: Perine left the Redskins’ Week 16 game early due to an Achilles tendon injury, and it appears the injury flared up again early in Week 17. The running back left the game during the first quarter, and the club declared him questionable to return. Early in the second half, the Redskins downgraded him to out.